Acute Thrombophlebitis (48000-41000)
This slide shows a vessel with thrombosis and acute inflammation of the vessel wall. In this low power view, note the thrombus in the lumen and the infiltrate in the wall.

Acute Thrombophlebitis (48000-41000)
This higher power view demonstrates that the thrombus is attached to the wall and the inflammatory infiltrate is predominantly neutrophilic. The major predisposing factors to the development of thrombosis are hypercoagulable states, stasis, and endothelial damage. Many cases of phlebothrombosis (thrombus in a vein) show only thrombus in the vessel lumen, but thrombosis in a vein may be accompanied by inflammatory changes in the vessel wall (thrombophlebitis). The chief clinical danger associated with venous thrombosis is embolization.