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Cardiovascular
Pathology for Medical II Students
Lab 3a Coronary Artery Atherosclerosis
Slides 43-35102 A & B | Slides 43-35102 C & D | Slide 3-1
Plaque Core (43-35102)
The core of the plaque contains many foamy, lipid-filled macrophages. Eccentric, lipid-rich atherosclerotic plaques are at risk of fissuring due to vessel spasm or changes in blood flow or pressure. Fissuring of the plaque frequently leads to superimposed thrombosis, with acute partial or total occlusion of the vessel lumen. Another mechanism of acute occlusion is hemorrhage into the plaque.
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Thrombosis (43-35102)
The lumen of this coronary artery is almost completely occluded by recent thrombus. Occlusion of flow will result in infarction of the myocardium if flow is not restored within 20-40 minutes. A thrombus may lyse spontaneously or may fragment and embolize to smaller caliber vessels. Thrombolytic therapy is currently an important part of management of acute myocardial infarction. |
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Digital Legends for Labs/Cases
Lab 1
1.a | 1.b | 1.c | 1.d | 1.e | 1.f | 1.g
Lab 2
2.a | 2.c | 2.e | 2.f | 2.g | 2.h | 2.i
Lab 3
3.a | 3.b | 3.c | 3.d | 3.e | 3.f | 3.g | 3.h
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Medical II
Updated
February 19, 2009
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