CNS Pathology for Medical II Students

Lab 1e Slides 25.1-25.3--Medulloblastoma

This is a malignant tumor in children that arises in the cerebellum usually in the vermis. The histology of this tumor is characterized by extreme cellularity and little stroma. The tumor cells are primitive neuroectodermal in nature and may differentiate to both neuronal and glial elements. These tumors grow into the fourth ventricle causing obstructive hydrocephalus and also frequently spread along the CSF pathways.

Slides 25.1 & 25.2 | Slide 25.3

Slide 25.3 Low power view of the spinal cord showing subarachnoid dissemination of medulloblastoma. The spinal roots are diffusely infiltrated by tumor cells.

Digital Legends for Labs/Cases
Lab 1
1.a | 1.b | 1.c | 1.d | 1.e

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Medical II

Updated August 28, 2007