(17) Syphilitic Aneurysm of the Aortic Arch: In tertiary syphilis, inflammation of the adventitia and the vasa vasorum of the aorta lead to weakening of the media and gradual aneurysm formation. These aneurysms typically affect the arch of the aorta, and may involve the root of the aorta, leading to incompetence of the aortic valve. Complications include compression or erosion of adjacent structures as well as rupture
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