HISTOGENESIS OF TESTICULAR NEOPLASMS (PEAK INCIDENCE)

GERM CELL PRECURSOR

SEMINOMA

(40-50 Y)

GONADAL

DIFFERENTIATION

EMBRYONAL CA

(UNDIFFERENTIATED)

(20-30 Y)

TOTIPOTENTIAL

DIFFERENTIATION

(NONSEMINOMA)

CHORIOCARCINOMA

(20-30 Y)

hCG +

TROPHOBLASTIC

DIFFERENTIATION

YOLK SAC TUMOR

(< 3 Y)

AFP +

YOLK SAC

DIFF

TERATOMA

(20-30 Y)

MATURE

IMMATURE

MALIGNANT TX

SOMATIC

DIFFERENTIATION

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