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ELECTRON MICROSCOPY FOR PATHOLOGISTS

Melanoma

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Case 33-A 
Cytoplasm contains various melanosomes, round to oval with tiny granules, some darkly staining and "corn cob" appearing premelanosomes, nuclei are indented, nucleoli are prominent, cellular interdigitation occurs without junctions.

Case 33-A
   

Case 33-B
Higher magnification showing premelanosomes with corn-cob appearance.

 

 

Case 33-B

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