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Electron Microscopy for Pathologists: Kidney Pathology
G. Focal segmental glomerulosclerosis with inclusions 
suggestive of Fabry's disease 

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Fabry's disease (angiokeratoma corporis diffusum) is a lysosomal storage disease or lipidosis with accumulation of glycolipids in the kidneys, heart and vessel walls of many organs. Lamellated lipid inclusions (myeloid bodies) are present within the visceral epithelial cells. This finding suggests the presence of Fabry's disease.





Focal segmental glomerulosclerosis

Next Lupus nephritis WHO class IV

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