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Electron Microscopy for Pathologists: Muscle Pathology
D2. Inclusion Body Myositis continued
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Image 5 of 7
Myelin figures. (Low magnification) Inclusion body myositis is
also characterized by disruption of myofibrils with subsarcolemmal
inclusions consisting of myelin figures (membranous whorls or
myeloid bodies).
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6 of 7
Myelin figures. (High magnification) At higher power, a
variety of myelin figures are displayed. |
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Image 7
of 7 Myelin figures. In addition to fibrillary material,
myelin figures (membranous whorls or myeloid bodies) are seen in
cases of inclusion body myopathy. In this case, the myofibrils
have been disrupted by the presence of multiple myelin figures of
varying size and shape.
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Glycogen accumulation and McArdle's Disease
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