Gastrointestinal Pathology for Medical II Students

Lab 1a Chronic Pancreatitis (59000-43000) 

Chronic pancreatitis is characterized by patchy fibrous replacement of whole lobules or parts of lobules, focal fat necrosis in different stages, and chronic inflammation.  Grossly, depending on the etiology and degree of injury, the gland may be slightly firm but have a normal outline, lobular pattern, and color.  Severe cases may be smaller than normal, bosselated, rock-hard, and display foci of fat  necrosis, calcification, or fully developed calculi.

Slide 1
Gross:  This chronically inflamed pancreas is small and scarred.  The dilated pancreatic duct contains a stone (arrow). Chronic Pancreatitis with stone

Chronic Pancreatitis with stone

Slide 2

X-ray:  This is an example of chronic pancreatitis with marked calcification of the pancreatic parenchyma. This calcification could be demonstrated by an x-ray of the abdomen.


Chronic Calcific Pancreatitis X-ray

Slide 3

Gross:  These are cross sections taken through the head of the pancreas in chronic pancreatitis.  The sections of pancreas which you have in your class sets were taken in a similar fashion.  Notice that the dense white fibrous scarring has almost totally obliterated the lobular architecture of the pancreas.


Chronic Pancreatitis Gross

Slide 4

This is a low magnification picture of the H&E slide of chronic pancreatitis in your class set.  This particular patient had an obstructive type of pancreatitis due to carcinoma of the head of the pancreas.  The lobular architecture of the pancreas is accentuated by broad bands of interstitial fibrosis.

Chronic Pancreatitis Scan: H&E

Digital Legends for Labs/Cases
Lab 1
1.a | 1.b | 1.c | 1.d | 1.e | 1.f | 1.g | 1.h | 1.i | 1.j | 1.k | 1.l | 1.m
Lab 2
2.a | 2.b | 2.c | 2.d | 2.e | 2.f | 2.g | 2.h | 2.i | 2.j | 2.k | 2.l | 2.m
Lab 3
3.a | 3.b | 3.c | 3.d | 3.e | 3.f | 3.g | 3.h | 3.i | 3.j | 3.k | 3.l

Medical II


Updated January 9, 2009