Gastrointestinal Pathology for Medical II Students

Lab 1f Squamous Cell Carcinoma of the Esophagus (62000-80713)

Slide 1
Gross: This is an example of an ulcerated squamous cell carcinoma of the esophagus. It differs from a benign peptic ulcer of the esophagus in that it is a much larger lesion and rather than being sharply punched-out, it has irregular borders. Note the perforation in the center.

perforation

Slide 2
Is a low power view of the histologic section in your class set. (M = mucosa; Sm = submucosa; Mp = muscularis propria). The intact mucosa is to the left of the arrow; the ulcerated carcinoma (C) is to the right.

mucosa

Slide 3
Is taken at the juncture (arrow head) of the normal mucosa (M) and the ulcerated carcinoma (C) and it shows another common feature of esophageal cancer. The gross margins of the cancer are often misleading because the tumor frequently spreads longitudinally in submucosal lymphatics (double arrows).

esophageal cancer
Slide 4
Is
a section taken through the full thickness of the esophageal wall. Carcinomas of the esophagus are typically deeply infiltrating lesions and this one has extended through the muscularis propria (arrows).
muscularis propria

Digital Legends for Labs/Cases
Lab 1
1.a | 1.b | 1.c | 1.d | 1.e | 1.f | 1.g | 1.h | 1.i | 1.j | 1.k | 1.l | 1.m
Lab 2
2.a | 2.b | 2.c | 2.d | 2.e | 2.f | 2.g | 2.h | 2.i | 2.j | 2.k | 2.l | 2.m
Lab 3
3.a | 3.b | 3.c | 3.d | 3.e | 3.f | 3.g | 3.h | 3.i | 3.j | 3.k | 3.l

Medical II


Updated March 2, 2007