Musculoskeletal & Skin Pathology for Medical II Students

Spring 2008 Lab Supplement
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Arthritis 1

Case History Normal Diarthrosis Slide 1: A hatchet accidentally fell on the left hand of a healthy 26- year-old man and severed four of the fingers. There was no past history of rheumatoid or other articular disease.

Case History Normal Diarthrosis Slide 2: Same as that for Slide 1.

Case History Normal Synovial Membrane Slide 3: A 63-year-old woman with diabetes mellitus of 12 years duration required a low thigh amputation for gangrene of the left foot. The left knee joint was dissected and no gross abnormalities were found. Aspiration produced 0.5 cc of clear, viscous, synovial fluid which contained 150 white blood cells and 1,600 red blood cells per ml. Such synovial findings are within normal limits.

Slides 1 & 2 | Slide 3

Slide 1 This is a mid-sagittal celloidin section of a distal interphalangeal joint. Note the congruity of the opposing cartilaginous surfaces.
Slide 2 This slide shows the articular margin of the distal phalanx in slide 1 under higher magnification. The surface of the cartilage is smooth. The chondrocytes are regularly arranged. The hyaline matrix is homogeneous and the subchondral bony plate is intact.

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Updated September 15, 2008