Slide 13A
Fatty change--liver. The cytoplasm has a foamy appearance due to the presence of minute fat globules. As the amount of fat increases these globules coalesce producing larger and larger globules. The reagents used to process the sections are fat solvents, so what you see is the space the fat occupied.

Slide 13B
Fatty change--liver. The cell membrane ruptures, liberating fat from a group of cells to coalesce into an extracellular lake of fat. This is recognizable as a large space between the liver cells.