Pathogenesis for Medical II Students

Lab 2 Cellular Adaptation & Minerals and Pigments (continued)

Slide 362A & 55B | Slide 55C & 30B

Slide 55C
Coronary artery with atherosclerosis. In the wall of the artery you can see foci which are staining darker blue. The blue color is due to the deposition of calcium, known as dystrophic calcification. It occurs in tissue already damaged by disease; in the presence of a normal blood calcium level. This image shows macrophages containing lipid material.


atheroma

Slide 30B
Chronic passive congestion - lung . Macrophages are present in the alveolar spaces. The cytoplasm in many of them is staining yellow-brown. This is due to the presence of hemosiderin. Hemosiderin is formed from hemoglobin derived from broken down red blood cells, which have been phagocytosed by macrophages. Hemosiderin is stained brown. Exogenous pigment (carbon or coal dust) is stained black. 

 

chronic passive congestions

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Updated June 27, 2008