Slide 1.23
The tissue comes from four biopsies so the amount of material and the number of glomeruli vary. All, however, show a proliferative lesion (mesangial in nature) with exudate of polymorphs, and in general, there is lobular accentuation of glomeruli. C3 and IgG were seen on immunofluorescence and all glomeruli had typical subepithelial electron-dense deposits on electron microscopy. These patients had clinical and other evidence indicating that the original disease was streptococcal in nature.