Renal Pathology for Medical II Students

Lab 1.h Diabetic Glomerulosclerosis
This material comes from a long standing diabetic who first became nephrotic and then went into renal failure with subsequent dialysis. Things to note are 1) the sclerotic condition of most glomeruli leading to renal failure 2) arterial and arteriolar thickening 3) chronic interstitial inflammation.

Slides 1.44 & 1.45 | Slides 1.46 & 1.47

Slide 1.44
This glomerulus (from another case) is an example of diffuse diabetic glomerulosclerosis. The mesangium is markedly increased without an increase in cellularity. Because the lesion is not that far advanced, peripheral capillary loops still contain patent capillary lumina.

 glomerulus
Slide 1.45
Acellular nodules of diabetic glomerulosclerosis (Kimmelstiel-Wilson lesion).

 

 glomerulosclerosis

Digital Legends for Labs
Lab 1 Images
2-5 | 6-8 | 10-12 | 23-24 | 27-28 | 30-31 | 38-41 | 44-47 | CM1 | CM2 | DC
Lab 2 Images
50-52 | 54-56 | 62-64 | 75-76 | 79-81 | 83-85 | 87-88 | 90-92 | 98-99

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Medical II

Updated August 2, 2007