Respiratory Pathology for Medical II Students

Lab 3.a Hyaline Membrane Disease (glass slide 28200-55020)

Slides A & B | Slide C

Slide A
In this low power view, the airspaces appear irregular in shape, with thickened walls. This apparent thickening is caused by alveolar septa collapsed against one another; the residual airspaces are mostly alveolar ducts and some proximal alveoli, while most of the peripheral alveoli are unexpanded.

airspaces

Slide B
This view shows a respiratory bronchiole opening into an alveolar duct that is lined by a hyaline membrane. The apparent cellularity of the adjacent alveolar parenchyma is caused by the marked atelectasis and immaturity of the lung tissue.

bronchiole

*Question:

1.What is the pathogenesis of hyaline membrane disease? 

Digital Legends for Labs/Cases
Lab 1
1.a | 1.b | 1.c | 1.d | 1.e | 1.f | 1.g | 1.h
Lab 2
2.a | 2.b | 2.c | 2.d | 2.e | 2.f | 2.g
Lab 3
3.a | 3.b | 3.c | 3.d | 3.e

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Updated August 3, 2007