VCU Service

Professor of Pathology and Director of Neuropathologyand Director of Neuropathology Fellowship Program, 2008-Present

Education

Undergraduate Education
Syracuse University  Syracuse, NY (1987-1991)
Degree: Bachelor of Science in Biology

Graduate Education
State University of NY Upstate Medical University   Syracuse, NY
{Formerly SUNY Health Science Center at Syracuse} (1991-1995)
Degree: Doctor of Medicine

Residency:                   
SUNY Upstate Medical University    Syracuse, NY
(1995-1999)
Anatomic / Clinical Pathology
Chief Resident- 1998-1999

Surgical Pathology Fellowship:                         
Washington University School of Medicine / Barnes-Jewish Hospital
Saint Louis, MO
1999-2000

Neuropathology Fellowship:                             
Washington University School of Medicine / Barnes-Jewish Hospital
Saint Louis, MO
2000-2002

Special Awards

Fellow- American Brain Tumor Association Research Fellowship Award

Professional Memberships / Organizations

Current member:
American Society of Clinical Pathologists
College of American Pathologists
United States and Canadian Academy of Pathology
American Association of Neuropathologists
Society for Neuro-Oncology
Children’s Oncology Group
Pediatric Brain Tumor Consortium

Books / Texts

Fuller CE, Threatte GA, Henry JB-  Chapter 18 “Basic examination of urine” for the 20th edition of Clinical Diagnosis and Management by Laboratory Methods , 2001, p367-402, W B Saunders, Philadelphia

Tu PH, Fuller C, Perry A.  Chapter 14: Molecular Diagnostics of CNS Tumors and Neurodegenerative Diseases.  In: Pfeifer J (ed.) Molecular Genetic Testing in Surgical Pathology, 2006, Lippincott Williams & Wilkins, Philadelphia, PA. 

Selected publications

King RB, Fuller C, Collins GH.  Delayed onset of hemidystonia and hemiballismus following head injury: A clinicopathological correlation. J Neurosurg 2001;94:309-314.

Fuller C, Schelper R, Miller DC, Smith M.  Pigmented papillary epithelial neoplasm of the pituitary fossa: A distinctive lesion with aggressive potential. Arch Pathol Lab Med 2001;125:1242-1245.

Lieberman KA, Fuller CE, Caruso RD, Schelper RL.  Postiradiated glioblastoma multiforme with osteosarcomatous components. Am J Neurorad 2001;43(7):555-8

Perry A, Roth KA, Banerjee R, Fuller CE, Gutmann DH.  NF1 deletions in S100-positive and negative cells of sporadic and neurofibromatosis 1 (NF1)-associated plexiform neurofibromas and MPNSTs. Am J Pathol 2001;159(1):57-61         

Fuller CE, Schelper R, Frankel B, Smith M, Rodziewitz G, Landas S, Caruso RD.  Suprasellar monomorphous pilomyxoid neoplasm: An ultrastructural analysis. Clin Neuropathol 2001;20:256-262

Fuller CE, Pfeifer J, Humphrey P, Bruch LA, Dehner LP, Perry A. Chromosome 22 alterations in composite extrarenal rhabdoid tumors: Clonal evolution or a phenotypic mimic? Hum Pathol 2001;32:1102-1108

Singh PK, Gutmann DH, Fuller CE, Newsham IF, Perry A. Differential involvement of protein 4.1 family members, DAL-1 and NF2 in intracranial and intraspinal ependymomas.  Mod Pathol 2002;15(5):526-531

Fuller CE, Wang H, Zhang W, Fuller GN, Perry A. High-throughput molecular profiling of high-grade astrocytomas: Utility of fluorescence in-situ hybridization on tissue microarrays (TMA-FISH). J Neuropathol Exp Neurol 2002;61(12):1078-1084

Perry A, Fuller CE, Banerjee R, Brat DJ, Scheithauer BW.  Ancillary FISH analysis for 1p and 19q status: preliminary observations in 250 gliomas and oligodendroglioma mimics. Front Biosci 2003;8:a1-9

Fuller CE, Schmidt RE, Roth KA, Burger PC, Scheithauer BW, Banerjee R, Trinkaus K, Lytle R, Perry A.  Clinical utility of fluorescence in situ hybridization (FISH) in morphologically ambiguous gliomas with hybrid oligodendroglial / astrocytic features. J Neuropathol Exp Neurol 2003;62(11):1118-1128

Fouladi M, Helton K, Dalton J, Gilger E, Gajjar A, Merchant T, Kun L, Newsham I, Burger P, Fuller C.  Clear cell ependymoma: A clinicopathologic and radiographic analysis of 10 cases. Cancer 2003:98:2232-2244

Gajjar A, Hernan R, Kocak M, Fuller CE, Lee Y, McKinnon PJ, Wallace D, Lau C, Chintagumpala M, Ashley D, Kellie S, Kun L, Gilbertson R. Clinical, histopathological and molecular markers of prognosis: toward a new disease risk stratification system for medulloblastoma. J Clin Oncol 2004;22(6):984-93.

Helton KJ, Fouladi M, Boop FA, Perry A, Dalton J, Fuller C.  Medullomyoblastoma: A radiographic and clinicopathologic analysis of 6 cases, and review of the literature. Cancer 2004;101:1445-54.

Romer J, Kimura H, Magdaleno S, Fuller C, Baines H, Connelly M, Gould S, Rubin L, Curran T.  Suppression of the Shh pathway using a small molecular inhibitor eliminates medulloblastoma in Ptc+/- p53-/- mice.  Cancer Cell 2004;6(3):229-240.           

Tekautz T, Fuller C, Fouladi M, Broniscer A, Merchant T, Krasin M, Dalton J, Hale G, Kun L, Wallace D, Gilbertson R, Gajjar A.  Atypical teratoid/rhabdoid tumors (ATRT): Improved survival in children 3 years of age and older with radiation therapy and high-dose alkylator-based chemotherapy. J Clin Oncol 2005;23(7):1491-9.

Perry A, Fuller CE, Judkins AR, Dehner LP, Biegel JA. Ini1 expression is retained in composite rhabdoid tumors, including rhabdoid meningiomas. Mod Pathol 2005;18:951-958.

Garrett KM, Fuller CE, Santana VM, Shochat SJ, Hoffer FA. Percutaneous biopsy of pediatric solid tumors. Cancer 2005;104:644-652

Kaste SC, Fuller CE, Saharia A, Neel MD, Rao BN, Daw NC. Pediatric Surface Osteosarcoma: Clinical, Pathologic, and Radiologic Features. Pediatr Blood Cancer 2005; Aug25 (epub ahead of print)

Taylor MD, Poppleton H, Fuller C, Su X, Liu X, Jensen P, Magdelano S, Dalton J, Board J, MacDonald T, Rutka J, Guha A, Gajjar A, Curran T, Gilbertson RJ. Radial glia cells are candidate stem cells of ependymoma. Cancer Cell 2005;8:323-335.

Thompson MC, Fuller C, Hogg T, Dalton J, Finkelstein D, Lau C, Chintagumpala M, Adesina A, Ashley DM, Kellie SJ, Taylor MD, Curran T, Gajjar A, Gilbertson RJ.  Genomics identifies medulloblastoma subgroups that are enriched for specific genetic alterations. J Clin Oncol 2006;24(12):1924-31 Epub 2006 Mar 27.

Sasai K, Romer JT, Lee Y, Finkelstein D, Fuller C, McKinnon PJ, Curran T. Shh pathway activity is down-regulated in cultured medulloblastoma cells: implications for preclinical studies. Cancer Res 2006;66(8):4215-4222.

Fuller C, Helton K, Dalton J, Fouladi M, Jun L, Burger P.  Polar spongioblastoma of the spinal cord:  A case report.  Pediatr Dev Pathol. Jan-Feb 2006; 9(1):75-80.

Fuller C, Fouladi M, Gajjar A, Dalton J, Sanford RA, Helton K . Chromosome 17 abnormalities in pediatric neuroblastic tumor with abundant neuropil and true rosettes. Am J Clin Pathol 2006;126(2):277-283.

Laurie N, Donovan S, Gray J, Fuller C, Johnson D, Wilson M, Rodriguez-Galindo C, Marine J-C, Jochemsen AG, Mendrysa S, Dyer MA. Inactivation of the p53 pathway in retinoblastoma.  Nature, 2006; 444(7115):61-66.

Broniscer A, Baker SJ, West AN, Fraser MM, Kocak M, Dalton J, Zambetti GP, Gajjar A, Gilbertson RJ, Fuller CE. Clinical and molecular characteristics of malignant transformation of low-grade glioma in children: the St. Jude Children’s Research Hospital experience. J Clin Oncol 2007;25:682-689.

Zhang J, Dalton J, Fuller C.  Epithelial marker-negative desmoplastic small round cell tumor (DSRCT) with atypical morphology:  definitive classification by fluorescence in situ hybridization. Arch Pathol Lab Med 2007;131:646-649.

Francis L, Bonilla E, Soforo E, Neupane H, Nakhla H, Fuller C, Perl A. Fatal toxic myopathy attributed to propofol, methylprednisolone, and cyclosporine after prior exposure to colchicine and simvastatin. Clin Rheumatol 2008;27:129-131.
Fuller CE and Perry A.  Low and intermediate grade gliomas.  J Rad Onc 2001;11(2):95-102

Pavlot  E, Butts S, Holsapple J, Fuller C. Aggressive pediatric meningioma with soft tissue and lymph node metastases: a case report. Pediatr Dev Pathol 2008 Dec 16:1 (Epub ahead of print)

Fuller CE and Perry A.  Fluorescence in-situ hybridization (FISH) in diagnostic and investigative neuropathology. Brain Pathol 2002;12:67-86

Fuller CE and Perry A.  Genetic adjuncts to diagnosis and prognostication in central nervous system tumors: the clinical utility of molecular characterization.  Adv Anat Pathol 2005;12:180-194.

Invited presentations / symposiums

“FISHing for answers in pediatric gliomas”- Beaumont Hospital, Dublin, Ireland.  November 2005.

"CNS Trauma" - University of Rochester, Rochester, NY - Oct 2007