VCU Service

Vice-Chair for Research and Graduate Education, 1999 - Present
Professor of Surgery (Affiliate Appointment), 1999 - Present
Professor of Human Genetics (Affiliate Appointment), 1999 - Present
Professor of Pathology, 1997 - Present
Professor of Physiology (Affiliate Appointment)
Associate Professor of Pathology, 1987 - 1997
Associate Professor of Physiology (Affiliate Appointment) 1994
Director, Athymic Nude Mouse Core Facility, 1987-1994 (Breeding colony established 1987)
Member, IACUC Virginia Commonwealth University

Other Significant Service

Ad Hoc Reviewer for: Cancer Research, International Journal of Cancer, Prostate, American J. Pathology, Invasion and Metastasis, J. Urology. Clinical Cancer Research, Invasion and Metastasis.

Organizer of workshop, "Prostate Cancer in Minority Populations: Biological Factors", held in Richmond, VA, June 2-3, 2000, Sponsored by Office for Research on Minority Health, NIH.

Education

Postdoctoral Training or Special Experience
NIH Postdoctoral Fellow, Department of Surgery, Division of Urology
Duke University Medical Center, Durham, NC, 1980 - 1981

NIH Postdoctoral Fellow, Sidney Farber Cancer Institute,
Boston, MA, 1979 - 1980 

NSF Predoctoral Fellow, Department of Bacteriology and Immunology
University of North Carolina, Chapel Hill, NC, 1976 - 1979

NIH Predoctoral Fellow, Department of Bacteriology and Immunology, University of North Carolina, Chapel Hill, NC, 1975 - 1976

Graduate and Undergraduate Education
PhD, University of North Carolina at Chapel Hill, 
Department of Microbiology and Immunology
Chapel Hill, NC 1979

BA, University of North Carolina at Chapel Hill
BA (Zoology), with highest honors
Chapel Hill, NC 1975

Professional Panels, Boards and Councils

NCI - Special Study Section: Developing Programs in Prostate Cancer, July, 1995

Consultant, NCI Cancer Center Core Grant Site Visit Team, 10/27/96 - 10/29/96

Consultant, DOD-Army Breast Cancer Research Program, 9/18/96 - 9/20/96

Invited participant, Workshop Conference on Endocrine Therapy in Advanced Prostate Cancer: Biological and Clinical Role of Estrogens sponsored by UVA Cancer Center, 1996

Invited participant, WHO Workshop on Animal Models of Prostate Cancer, Purdue University, 1997

Chair, US Army Prostate Cancer Cell Biology Study Section I, 1998

Ad Hoc Member, NIDDK Urology Special Emphasis Panel, 1998

Metabolic Pathology Study Section, NCI Ad-Hoc Reviewer, October, 1998

NCI Cancer Center Site Visit Team, 1998

Ad Hoc Reviewer, Extramural Review of VA Merit Awards, Veterans Administration
Medical Review Board, 1994 - 1998 

Chair, US Army Prostate Cancer Cell Biology Study, Section I, January, 1999

Permanent Member, NIDDK Urology Special Emphasis Panel, 1999-2003

Chair, US Army Prostate Cancer Cell Biology Study Section 1, May, 2000

Professional & Community Service

President, Women in Cancer Research 1998-1999
AACR Membership Committee 1996-1997
AACR Program Committee, Tumor Biology Subcommittee, 1998/99
AACR Educational Program Committee, 1998/99
AACR, Chair of AACR Fellowship Grant Committee, 1999/2000
Co-Director Mini-Medical School, Science Museum of Virginia

Professional Organizations

Wildlife Disease Association
Virginia Herpetological Society, Chair of Research Committee
American Association for Cancer Research
American Association for Advancement of Science
Women in Cancer Research (Program Chair, 1990; President-elect 1997; President, 1998)

Recent Publications

Clark AJ, Dos SW, McCready J, Chen MY, Van Meter TE, Ware JL, Wolber SB, Fillmore H, Broaddus WC. Wilms tumor 1 expression in malignant gliomas and correlation of +KTS isoforms with p53 status. J Neurosurg. 2007 Sep;107(3):586-92.

Redmond LC, Haar JL, Giebel ML, Dumur CI, Basu P, Ware JL, Lloyd JA. Isolation of erythroid cells from the mouse embryonic yolk sac by laser capture microdissection and subsequent microarray hybridization. Blood Cells Mol Dis. 2006 Jul-Aug;37(1):27-32. Epub 2006 May 12.

York TP, Plymate SR, Nelson PS, Eaves LJ, Webb HD, Ware JL. cDNA microarray analysis identifies genes induced in common by peptide growth factors and androgen in human prostate epithelial cells. Mol Carcinog. 2005 Dec;44(4):242-51.

Chen N, Szentirmay MN, Pawar SA, Sirito M, Wang J, Wang Z, Zhai Q, Yang HX, Peehl DM, Ware JL, Sawadogo M. Tumor-suppression function of transcription factor USF2 in prostate carcinogenesis. Oncogene. 2006 Jan 26;25(4):579-87.

Koochekpour S, Zhuang YJ, Beroukhim R, Hsieh CL, Hofer MD, Zhau HE, Hiraiwa M, Pattan DY, Ware JL, Luftig RB, Sandhoff K, Sawyers CL, Pienta KJ, Rubin MA, Vessella RL, Sellers WR, Sartor O. Amplification and overexpression of prosaposin in prostate cancer. Genes Chromosomes Cancer. 2005 Dec;44(4):351-64.

Ware JL. What can proteomic analyses contribute to understanding the molecular biology and clinical behavior of prostate cancer? Expert Rev Proteomics. 2004 Dec;1(4):485-92. Review.

Plymate SR, Tennant MK, Culp SH, Woodke L, Marcelli M, Colman I, Nelson PS, Carroll JM, Roberts CT Jr, Ware JL. Androgen receptor (AR) expression in AR-negative prostate cancer cells results in differential effects of DHT and IGF-I on proliferation and AR activity between localized and metastatic tumors. Prostate. 2004 Nov 1;61(3):276-90.

Huang D, Liu X, Plymate SR, Idowu M, Grimes M, Best AM, McKinney JL, Ware JL. Proteomic identification of 14-3-3 sigma as a common component of the androgen receptor and the epidermal growth factor receptor signaling pathways of the human prostate epithelial cell line M12. Oncogene. 2004 Sep 9;23(41):6881-9.

Liu, X., Wu, Y, Zehner, Z, Jackson-Cook, C, and Ware, JL : Proteomic analysis of the tumorigenic human prostate cell line M12 after microcell-mediated transfer of chromosome 19 demonstrates reduction of vimentin.  Electrophoresis, 24: 3445-3453, 2003.

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Updated February 6, 2008