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GRAND ROUNDS PRESENTATION
 

"Laboratory Diagnoses of Diseases Past and Present"
 

Dr. Youngman Oh & Dr. Marvin AllisonDuring Grand Rounds Friday October 1, Marvin J. Allison, PhD, Professor of Pathology, Virginia Commonwealth University presented a discussion concerning the study of Laboratory Diagnoses of Diseases Past and Present.  His lecture incorporated images from rare mummified tissues examined in the Paleopathology Laboratory, a world-renowned center for the study of soft human tissue which also provides consultation to specialists and students in many branches of medicine.  When asked about this unique research, Dr. Allison provided the following summary:

"Dr. Enrique Gerszten and I have worked together for the past 43 years. Our first area of research was in the field of tuberculosis taking advantage of an excellent sanatorium at the Medical College of Virginia Hospital. Our work concerned the factors associated with resistance to tuberculosis, resistance to M. tuberculosis therapy, pulmonary disease due to the unclassified Mycobacterium, and changes in pathology associated with the chemotherapy of tuberculosis. The sanatorium closed during the late sixties, and money for tuberculosis research dried up since all the agencies were convinced (erroneously) that it was no longer a problem.

We then focused our research on pre-Columbian Andean diseases. I had previously worked a number of years in Peru and had contacts in the region, which allowed us to work with local archaeologists, and to autopsy the sun dried bodies that the archaeologists discarded as of no use to them. We studied organ and bone disease using modern hospital technology and published over one hundred scientific papers and as many presentations, often with posters, at national and international congresses of pathology. Basically we found that the diseases of man in modern Peru were also present in pre-Columbian Peru. We also learned that "persister" virus diseases identified as late as 1989 were present 3000 years ago in Peru and still plague the modern Amazon Indians, killing them off before the age of 35.

During the last five years we have been using molecular diagnostic tools to study breast cancer. Our Department of Pathology is a center for the study of soft tissue disease paleopathology, and serves as a world consultation center. We also have sponsored a Paleopathology Club for the past 27 years associated with the International Academy of Pathology Congress, and we offer practical 35-mm slide diagnoses to our 700 world members in four newsletters annually. This work in Paleopathology has established Virginia Commonwealth University worldwide and has served as a source of public relations locally and in other American Universities."

For more information about Paleopathology contact Dr. Marvin Allison at
(804) 828-9746, FAX: (804) 828-9749, or email mallison@mail2.vcu.edu


Pathology Grand Rounds are held in the Sanger Hall Conference Room 4-026 every Friday, September-June, 12noon-1pm. A schedule is posted on the Pathology Web: http://www.pathology.vcu.edu/news/rounds.html

Nancy Dryden is the Pathology Grand Rounds Coordinator;  for information regarding
Pathology Grand Rounds please feel free to contact her at
(804) 828-0183 or nsdryden@vcu.edu

Updated 07 October 2004