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Breast Cancer Biology Laboratory

Laboratory Director

Lynne Elmore, PhDLynne Elmore, PhD, is an Assistant Professor in the Department of Pathology and a member of the Massey Cancer Center. She is the recipient of a NCI/NIH Howard Temin Award, 2005-2011; Department of Defense Breast Cancer Concept Awards, 2005-2006 & 2009-2010; a Department of Defense Breast Cancer Idea Award, 2010-2012; a Jeffress Memorial Trust Award, 2009-1011; and a 2011-2012 VCU Presidential Research Incentive Program Grant.  Dr. Elmore is also currently a Co-investigator on a National Institute of Nursing Research RO-1 grant (2010-2015; PIs: Drs. Lyon and Jackson-Cook). In addition, she has been the past recipient of a Department of Pathology Research award, a Massey Cancer Center breast cancer pilot project grant, and an institutional American Cancer Society Award.

Dr. Elmore’s research focuses on the contribution of stromal constituents in breast cancer progression and in particular the role of mesenchymal stem cells within mammary fat, with the hope of developing stromal-based targeted therapies. Current investigations also relate to elucidating the mechanisms of cellular aging in normal and Progeria cells as well as reprogramming patient-derived cells for studying mechanisms underlying the development of psychoneurologic symptoms in women with breast cancer post-chemotherapy.

Dr. Elmore completed her PhD in Pathology at Virginia Commonwealth University, Richmond, VA in 1993. Her Advisor was Alphonse Sirica, PhD. She did her postdoctoral training in the Laboratory of Human Carcinogenesis at the National Cancer Institute from 1993-1997. Her sponsor was Curt Harris, MD.


Research Staff

Molly Bristol

Currently a Post-Doc in the Elmore lab, Molly graduated with a B.S. in chemistry in 2006 before continuing on to receive her Ph.D. in Pharmacology and Toxicology from Virginia Commonwealth University in 2011.  Molly's project currently focuses on the role of HB-EGF in the development of fibrosis in breast MSCs. 

 


Jacqueline Merrill Schools

Currently a postdoctoral fellow in the Elmore lab, Jacqueline graduated with a Bachelors of Science in biology in 2001 from Virginia Tech.  She received a Masters of Science in 2005 from University of Virginia, and continued on to receive her PhD in Biochemistry and Molecular Genetics from UVA in 2009. Jacqueline's projects currently focus on reprograming adult stem cells as well as specialized cell types into induced pluripotent stem cells (IPSCs).  She is also focusing on aging and mechanisms involved in increasing lifespan in human cells.

 

Xu Wang

Received a Bachelor's Degree at Nanjing University in Nanjing, China. Xu joined the lab as a research specialist in January 2010. She is assisting on projects relating to various aspects of mammary carcinogenesis and stem cell biology.
Xu worked at Microbiology & Immunology and Psychatric department of VCU before the Lab.


Min Zhao Min Zhao

Received a Bachelor's Degree at Zhejin Medical University in Hangzhou, China. Min joined the lab as a research specialist in June '08. She is assisting on projects relating to various aspects of mammary carcinogenesis and stem cell biology.