Home > Research > Research Programs > Cellular and Molecular Pathogenesis
Cellular and Molecular Pathogenesis
The study
of cellular and molecular mechanisms of disease
 The Division of Cellular
and Molecular Pathogenesis, under the Chairmanship of Alphonse E.
Sirica, PhD, MS, fosters high quality scholarship and provides
strong predoctoral and postdoctoral training in investigative pathology,
with a primary emphasis on cellular and molecular mechanisms of disease.
Dr. Sirica is a Professor of Pathology and Internal Medicine. He is also directing the development of the GI Oncology Research Initiative within Virginia Commonwealth University School of Medicine.
He is in the twenty-fourth year of funding for his R01 grant Hepatic Oval Cells in Culture and In Vivo, which was renewed for five years in 2007. Additionally, Dr. Sirica is PI on a second RO1 grant from the National Cancer Institute entitled Altered Growth Factor Pathways in Biliary Cancer.
Research conducted
by Division faculty is supported by NIH grants and other sources of extramural
and intramural funding. The Division maintains modern and well-equipped
laboratories located primarily on the 4th floor of Sanger Hall. In addition,
it is supported by a number of core laboratories in the Department of
Pathology, including molecular diagnostics facilities.
The Division also oversees graduate research and education in the Department
of Pathology and has sponsored a number of nationally recognized training
workshops and symposia on the pathobiology of neoplasia. A number of textbooks
related to experimental pathology and to the pathobiology of neoplasia
have been generated by the Division, helping to support it's goal of training
researchers in investigative pathology and conducting innovative basic
cancer research. |
