| Recent Publications |
Z. Zhang, G-H. Lai, and A.E. Sirica. (2004). Clecoxib-induced apoptosis in rat cholangiocarcioma cells mediated by Akt inactivation and Bax translocation. 39:1028-1037.
Lai, G-H., Zhang, Z., and Sirica, A.E. (2003). Celecoxib acts in a cyclooxygenase-2-independent manner and in synergy with emodin to suppress rat cholangiocarcinoma growth in vitro through a mechanism involving enhanced Akt inactivation and increased activation of caspass-9 and 3. Molecular Cancer Therapeutics, 2:265-271.
Sirica, A.E., Lai, G-H., Endo, K., Zhang, Z. and Yoon, B.: 2002. Cyclooxygenase-2 and ERBB-2 in cholangiocarcinoma: Potential Therapeutic targets. In: Seminars in Liver Disease (G. Fitz, ed.) Invited Paper. 22:303-314.
A.E.Sirica, G-H. Lai and Z. Zhang. (2001). Biliary cancer growth factor pathways, cyclooxygenase-2 and potential therapeutic strategies. J. Gastroenterology and Hepatology, 16: 363-372.
G-H. Lai, S. Radaeva, T. Nakamura, & A.E. Sirica. (2000). Unique epithelial cell production of hepatocyte growth factor/scatter factor by putative precancerous intestinal metaplasias and associated "intestine-type" of biliary cancer chemically induced in rat liver. Hepatology, 31: 1257-65.
G-H Lai, & A.E. Sirica. (1999). Establishment and characterization of a novel rat cholangiocarcinoma culture model. Carcinogenesis, 20: 2335-39. |